• May 22, 2022
    Our undergraduate trainee Gandhar Mahadeshwar has graduated with honors in Molecular Biophysics and Biological Chemistry as well as Practical Mathematics.
  • April 3, 2022
    The Pyle lab has released AMIGOS III, the latest version of AMIGOS for pseudo-torsion angle-based analysis of RNA structures. The AMIGOS III paper is published in...
  • March 30, 2022
    We report the experimentally determined secondary structure of the HCV RNA genome in our recently published Journal of Virology paper titled “The In Vivo and In Vitro...
  • March 10, 2022
    The Pyle Lab would like to welcome Lucille Tsao!
  • November 25, 2021
    Our article entitled “Discovery of highly reactive self-splicing group II introns within the mitochondrial genomes of human pathogenic fungi” was published by Nucleic Acid...
  • November 10, 2021
    Our paper “A stem-loop RNA RIG-I agonist protects against acute and chronic SARS-CoV-2 infection in mice” published in Journal of Experimental Medicine was featured in...
  • September 12, 2021
    We published an article entitled “The molecular mechanism of RIG-I activation and signaling” to review the role of RIG-I in innate immunity against viral infection.